Role of Supercomputers in Biological Science

Role of Supercomputers in Biological Science

Supercomputers play an important role in the field of computational science, and are used for a wide range of computational tasks in various fields, including quantum mechanics, weather forecasting, climate research, oil and gas exploration, molecular modeling (computing the structures and properties of chemical compounds, biological macromolecules, polymers, and crystals), and physical simulations (such as simulations of the early moments of the universe, airplane and spacecraft aerodynamics, the detonation of nuclear weapons, and nuclear fusion).

Biological computers is an implantable device that is mainly used for tasks like monitoring the body’s activities or inducing therapeutic effects, all at the molecular or cellular level. This is made up of RNA, DNA and proteins and can also perform simple mathematical calculations.

High-performance computing (or HPC) enables discoveries in practically every field of science not just those typically associated with supercomputers like chemistry and physics, but also in the social sciences, life sciences and humanities.

Improving health and quality of life

1. Finding Cures for Hepatitis C 

Researchers from the Centers for Disease Control (CDC) created a far more detailed model of the hepatitis C virus, a major cause of liver disease.

Impact of HCV

According to the world health organization (WHO), about 150 million people are chronically infected by HCV, with 3 to 4 million new infections every year. 75% to 85% of newly infected individuals develop chronic disease with long-term complications, including liver cirrhosis and liver cancer. Since to date no vaccine is available and more than 350,000 patients die yearly from hepatitis C-related diseases, the virus poses a major health concern.

2. Lowering the Cost of Advanced Cancer Care 

HPC-driven cancer research enabled better outcomes for long-term survivors of cancer. Advances in cancer detection and treatment have led to large improvements in survival rates but with increased survival comes an increased need to minimize long-term treatment-related negative effects.

Pros of biological computers

The biological computers are a type of the biosensors which have emerged as the interdisciplinary field that draws together molecular biology , chemistry , computer science & mathematics Bio-computing is one of the new fields in research which deals with the computer science & biology , This enables the researcher to build an array of data accordingly , The development of bio-computers has been made possible by the expanding new science of nano-biotechnology.

Tyrone, in association with NVIDIA, offers Tesla Bio Workbench, a specialized HPC platform that aims to convert a scientist’s standard PC into a “computational laboratory” capable of running complex bioscience codes at unparalleled speed. Using NVIDIA’s massively parallel CUDA architecture, the Tesla Bio Workbench consists of the following:

A range of GPU-optimized bioscience applications for molecular dynamics and quantum chemistry- based research, including: AMBER, GROMACS, LAMMPS, NAMD, TeraChem, VMD, and bioinformatics applications like CUDASW++ (Smith-Waterman), GPU-HMMER, and MUMmerGPU.

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